{"id":2,"date":"2025-01-24T23:21:16","date_gmt":"2025-01-24T15:21:16","guid":{"rendered":"https:\/\/tiand.top\/?page_id=2"},"modified":"2025-08-03T22:36:07","modified_gmt":"2025-08-03T14:36:07","slug":"publications","status":"publish","type":"page","link":"https:\/\/tiand.top\/index.php\/publications\/","title":{"rendered":"Representative Publications"},"content":{"rendered":"\n<p class=\"has-text-align-center\">*\uff1aCo-first author; #\uff1aCo-corresponding author<\/p>\n\n\n\n<h4 class=\"wp-block-heading has-text-align-center\">Research Articles<\/h4>\n\n\n\n<p class=\"has-text-align-center\"><mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-heading-color\">Full publications can be seen in <a href=\"https:\/\/scholar.google.com\/citations?hl=en&amp;user=_iKgyWAAAAAJ&amp;view_op=list_works&amp;sortby=pubdate\" target=\"_blank\" rel=\"noreferrer noopener\">Google Scholar<\/a>.<\/mark><\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Huang S*, Pan L*, Pang S*, Guo H*, Li M, Tian Y, Shi W, Liu B, Wang S, Fan Z, Zong Y<sup>#<\/sup>, <strong>Tian D<\/strong><sup>#<\/sup>, Zhang D<sup>#<\/sup>. Perforin Generated by CD8+ T Cells Exacerbates Inflammatory Bowel Disease\u2013Induced Depression by Promoting CXCL9 Production in Intestinal Epithelial Cells. <mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-primary-color\"><em>Gastroenterology<\/em>. 2025<\/mark> Aug; 169(2): 294-307. <mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-heading-color\">(Front Cover)<\/mark> <mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-heading-color\">IF: 26.3<\/mark> <img decoding=\"async\" class=\"wp-image-354\" style=\"width: NaNpx;\" src=\"https:\/\/tiand.top\/wp-content\/uploads\/2025\/07\/20250321_Gastroenterology_Perforin-exacerbates-IBD-induced-depression_preproof-1.pdf\" alt=\"\"><a href=\"https:\/\/tiand.top\/wp-content\/uploads\/2025\/07\/20250321_Gastroenterology_Perforin-exacerbates-IBD-induced-depression_preproof.pdf\" target=\"_blank\" rel=\"noreferrer noopener\"><img loading=\"lazy\" decoding=\"async\" width=\"20\" height=\"25\" class=\"wp-image-153\" style=\"width: 20px;\" src=\"https:\/\/tiand.top\/wp-content\/uploads\/2025\/01\/PDF_file_icon.png\" alt=\"\" srcset=\"https:\/\/tiand.top\/wp-content\/uploads\/2025\/01\/PDF_file_icon.png 267w, https:\/\/tiand.top\/wp-content\/uploads\/2025\/01\/PDF_file_icon-244x300.png 244w\" sizes=\"auto, (max-width: 20px) 100vw, 20px\" \/><\/a>\n<ul class=\"wp-block-list\">\n<li>Link: <a href=\"https:\/\/news.ccmu.edu.cn\/syyw_12977\/d2fed541496b41368395a3fe8cea3763.htm\" target=\"_blank\" rel=\"noreferrer noopener\">Reported by Capital Medical University<\/a> (Chinese)<\/li>\n\n\n\n<li>Link: <a href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzA5Mjg2Mjg3NA==&amp;mid=2703170538&amp;idx=2&amp;sn=333dd25d898d7965bfc076390f89db68&amp;chksm=b5a788bdba16efa4b77e9849475ad09dd5a51b10b16dd93719871b19235cae676d2c6488ee7b&amp;mpshare=1&amp;scene=2&amp;srcid=0725MnO2ZFXBcEziA1D3ceVI&amp;sharer_shareinfo=4483cd81fbefcb25cea9245a674a0415&amp;sharer_shareinfo_first=334b295496e90e3914f7b9a30206924b#rd\" target=\"_blank\" rel=\"noreferrer noopener\">Reported by Beijing Friendship Hospital<\/a> (Chinese, detailed description)<\/li>\n\n\n\n<li>Link: <a href=\"https:\/\/www.stdaily.com\/web\/gdxw\/2025-07\/28\/content_376833.html\" target=\"_blank\" rel=\"noreferrer noopener\">Reported by stdaily.com\u4e2d\u56fd\u79d1\u6280\u7f51<\/a> (Chinese, science popularization)<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>Tian D<\/strong>, Yang L, Wang S, Zhu Y, Shi W, Zhang C, Jin H, Tian Y, Xu H, Sun G, Liu K, Zhang Z and Zhang D. Double negative T cells mediate Lag3-dependent antigen-specific protection in OVA-induced allergic asthma. <mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-primary-color\"><em>Nat Commun<\/em>. 2019<\/mark> Sep 18;10(1):4246. <mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-heading-color\">IF: 12.1<\/mark> <a href=\"https:\/\/tiand.top\/wp-content\/uploads\/2025\/01\/2019_nc_Double-negative-T-cells-mediate-Lag3-d-1.pdf\" target=\"_blank\" rel=\"noreferrer noopener\"><img loading=\"lazy\" decoding=\"async\" width=\"20\" height=\"25\" class=\"wp-image-153\" style=\"width: 20px;\" src=\"https:\/\/tiand.top\/wp-content\/uploads\/2025\/01\/PDF_file_icon.png\" alt=\"\" srcset=\"https:\/\/tiand.top\/wp-content\/uploads\/2025\/01\/PDF_file_icon.png 267w, https:\/\/tiand.top\/wp-content\/uploads\/2025\/01\/PDF_file_icon-244x300.png 244w\" sizes=\"auto, (max-width: 20px) 100vw, 20px\" \/><\/a>\n<ul class=\"wp-block-list\">\n<li>Link: <a href=\"https:\/\/www.nsfc.gov.cn\/csc\/20340\/20343\/46499\/index.html\" target=\"_blank\" rel=\"noreferrer noopener\">Reported by National Natural Science Foundation of China<\/a> (Chinese)<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li>Yang L*, Zhu Y*, <strong>Tian D*<\/strong>, Wang S*, Guo J, Jin H, Zhang C, Shi W, Sun G, Zhang Z, Zhao Y<sup>#<\/sup>, Zhang D<sup>#<\/sup>. Transcriptome landscape of double negative T cells by single-cell RNA sequencing. <mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-primary-color\"><em>J Autoimmun<\/em>. 2021<\/mark>; 121: 102653. <mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-heading-color\">IF: 14.5<\/mark> <a href=\"https:\/\/tiand.top\/wp-content\/uploads\/2025\/01\/2021_JA_Transcriptome-landscape-of-double-nega.pdf\" target=\"_blank\" rel=\"noreferrer noopener\"><img loading=\"lazy\" decoding=\"async\" width=\"20\" height=\"25\" class=\"wp-image-153\" style=\"width: 20px;\" src=\"https:\/\/tiand.top\/wp-content\/uploads\/2025\/01\/PDF_file_icon.png\" alt=\"\" srcset=\"https:\/\/tiand.top\/wp-content\/uploads\/2025\/01\/PDF_file_icon.png 267w, https:\/\/tiand.top\/wp-content\/uploads\/2025\/01\/PDF_file_icon-244x300.png 244w\" sizes=\"auto, (max-width: 20px) 100vw, 20px\" \/><\/a>\n<ul class=\"wp-block-list\">\n<li>Link: <a href=\"https:\/\/news.ccmu.edu.cn\/syyw_12977\/110587.htm\" target=\"_blank\" rel=\"noreferrer noopener\">Reported by Capital Medical University<\/a> (Chinese)<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li><strong>Tian D* <\/strong>, Pan Y<sup>*<\/sup>, Zhao Y, Wang H, Tian Y, Yang L, Shi W, Zhang C, Zhu Y, Zhang Y<sup>#<\/sup>, Wang S<sup>#<\/sup>, Zhang D<sup>#<\/sup>, TCR\u03b1\u03b2+NK1.1-CD4-CD8- double-negative T cells inhibit central and peripheral inflammation and ameliorate ischemic stroke in mice. <mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-primary-color\"><em>Theranostics<\/em>. 2023<\/mark>, 13(3): 896-909. <mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-heading-color\">IF: 12.4<\/mark> <a href=\"https:\/\/tiand.top\/wp-content\/uploads\/2025\/01\/2023_Theronostics_TCR\u03b1\u03b2NK1.1-CD4-CD8-double-negative-T-cells-inhibit.pdf\" target=\"_blank\" rel=\"noreferrer noopener\"><img loading=\"lazy\" decoding=\"async\" width=\"20\" height=\"25\" class=\"wp-image-153\" style=\"width: 20px;\" src=\"https:\/\/tiand.top\/wp-content\/uploads\/2025\/01\/PDF_file_icon.png\" alt=\"\" srcset=\"https:\/\/tiand.top\/wp-content\/uploads\/2025\/01\/PDF_file_icon.png 267w, https:\/\/tiand.top\/wp-content\/uploads\/2025\/01\/PDF_file_icon-244x300.png 244w\" sizes=\"auto, (max-width: 20px) 100vw, 20px\" \/><\/a><\/li>\n\n\n\n<li>Qi H* , <strong>Tian D* <\/strong>, Zhang C, Jin H, Wang Y, Liu L, Zhao X, Ma L, Duan T<sup>#<\/sup>, Zhang D<sup>#<\/sup>. Foxo3 promotes the differentiation and function of follicular helper T cells. <mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-primary-color\"><em>Cell Rep<\/em>. 2020<\/mark> May 12. <mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-heading-color\">IF: 8.1<\/mark> <strong> <a href=\"https:\/\/tiand.top\/wp-content\/uploads\/2025\/01\/2020_CellReports_Foxo3-Promotes-the-Differentiation_reduced-size.pdf\" target=\"_blank\" rel=\"noreferrer noopener\"><img loading=\"lazy\" decoding=\"async\" width=\"20\" height=\"25\" class=\"wp-image-153\" style=\"width: 20px;\" src=\"https:\/\/tiand.top\/wp-content\/uploads\/2025\/01\/PDF_file_icon.png\" alt=\"\" srcset=\"https:\/\/tiand.top\/wp-content\/uploads\/2025\/01\/PDF_file_icon.png 267w, https:\/\/tiand.top\/wp-content\/uploads\/2025\/01\/PDF_file_icon-244x300.png 244w\" sizes=\"auto, (max-width: 20px) 100vw, 20px\" \/><\/a> <\/strong>\n<ul class=\"wp-block-list\">\n<li>Link: <a href=\"http:\/\/ncrc-dd.org.cn\/Html\/News\/Articles\/3721.html\" target=\"_blank\" rel=\"noreferrer noopener\">Reported by Beijing Friendship Hospital<\/a> (Chinese)<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li>Li M*, Pan L*, Zhang Y*, Huang S, Tian Y, <strong>Tian D<sup>#<\/sup><\/strong>, Zhang D<sup>#<\/sup>. Regulatory TCR\u03b1\u03b2+ double negative T cells suppress \u03b3\u03b4 T cells and alleviate colitis. <mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-primary-color\"><em>Cell Mol Gastroenterol Hepatol<\/em>. 2025<\/mark>, 19(10): 101553. <mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-heading-color\">IF: 7.4<\/mark>. <strong><a href=\"https:\/\/tiand.top\/wp-content\/uploads\/2025\/07\/2025_CMGH_Regulatory-TCR\u03b1\u03b2-double-negative-T-cells-suppress-\u03b3\u03b4-T-cells-and-alleviate-colitis.pdf\" target=\"_blank\" rel=\"noreferrer noopener\"><img loading=\"lazy\" decoding=\"async\" width=\"20\" height=\"25\" class=\"wp-image-153\" style=\"width: 20px;\" src=\"https:\/\/tiand.top\/wp-content\/uploads\/2025\/01\/PDF_file_icon.png\" alt=\"\" srcset=\"https:\/\/tiand.top\/wp-content\/uploads\/2025\/01\/PDF_file_icon.png 267w, https:\/\/tiand.top\/wp-content\/uploads\/2025\/01\/PDF_file_icon-244x300.png 244w\" sizes=\"auto, (max-width: 20px) 100vw, 20px\" \/><\/a> <\/strong><\/li>\n\n\n\n<li>Pan L, Shen C, Huang S, Yang<em> Y<sup>#<\/sup>, Zhang<\/em> Z<em><sup>#<\/sup><\/em>, <strong>Tian D<sup>#<\/sup><\/strong>. Immunophenotyping of Mouse Colonic Unconventional T cells by Mapping Cell Phenomics with 22-Color Flow Cytometry Assays. <mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-primary-color\"><em>Phenomics<\/em>. 2025<\/mark> (Accepted). <mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-heading-color\">IF: 6.2<\/mark>.<\/li>\n\n\n\n<li>Xu L * , <strong>Tian D*  <\/strong>, Zhou M, Ma J, Sun G, Jin H, Li M, Zhang D<sup>#<\/sup>, Wu J<sup>#<\/sup>, OX40 expression in eosinophils aggravates OVA-induced eosinophilic gastroenteritis. <mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-primary-color\"><em>Front Immunol<\/em>. 2022<\/mark>; 13: 841141.  <mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-heading-color\">IF: 8.8 <\/mark><a href=\"https:\/\/tiand.top\/wp-content\/uploads\/2025\/01\/2022_OX40-Eos.pdf\" target=\"_blank\" rel=\"noreferrer noopener\"><img loading=\"lazy\" decoding=\"async\" width=\"20\" height=\"25\" class=\"wp-image-153\" style=\"width: 20px;\" src=\"https:\/\/tiand.top\/wp-content\/uploads\/2025\/01\/PDF_file_icon.png\" alt=\"\" srcset=\"https:\/\/tiand.top\/wp-content\/uploads\/2025\/01\/PDF_file_icon.png 267w, https:\/\/tiand.top\/wp-content\/uploads\/2025\/01\/PDF_file_icon-244x300.png 244w\" sizes=\"auto, (max-width: 20px) 100vw, 20px\" \/><\/a><\/li>\n\n\n\n<li>Li M*, Cheng H*, <strong>Tian D* <\/strong>, Yang L, Du X, Pan Y, Zhang D<sup>#<\/sup>, Mei X<sup>#<\/sup>, D-mannose suppresses \u03b3\u03b4 T cells and alleviates murine psoriasis. <mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-primary-color\"><em>Front Immunol<\/em>. 2022<\/mark>, 13: 840755. <mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-heading-color\">IF: 8.8<\/mark> <a href=\"https:\/\/tiand.top\/wp-content\/uploads\/2025\/01\/2022_Frontiers-in-Immu_D-Mannose-Suppresses-gd-T-Cells-and-Alleviates-Murine-Psoriasis.pdf\" target=\"_blank\" rel=\"noreferrer noopener\"><img loading=\"lazy\" decoding=\"async\" width=\"20\" height=\"25\" class=\"wp-image-153\" style=\"width: 20px;\" src=\"https:\/\/tiand.top\/wp-content\/uploads\/2025\/01\/PDF_file_icon.png\" alt=\"\" srcset=\"https:\/\/tiand.top\/wp-content\/uploads\/2025\/01\/PDF_file_icon.png 267w, https:\/\/tiand.top\/wp-content\/uploads\/2025\/01\/PDF_file_icon-244x300.png 244w\" sizes=\"auto, (max-width: 20px) 100vw, 20px\" \/><\/a><\/li>\n\n\n\n<li>Bu F* , Huang S* , Yang X, Wei L, Zhang D, Zhang Z<sup>#<\/sup>, <strong>Tian D<sup>#<\/sup><\/strong>. Damage-induced NAD Release Activates Intestinal CD4+ and CD8+ T cells via P2X7R Signaling. <mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-primary-color\"><em>Cell Immunol<\/em>. 2023<\/mark>; 385: 104677. <a href=\"https:\/\/tiand.top\/wp-content\/uploads\/2025\/01\/2023_Cell-Imm_Damage-induced-NAD-release-activates-intestinal-CD4-and-CD8-T-cell.pdf\" target=\"_blank\" rel=\"noreferrer noopener\"><img loading=\"lazy\" decoding=\"async\" width=\"20\" height=\"25\" class=\"wp-image-153\" style=\"width: 20px;\" src=\"https:\/\/tiand.top\/wp-content\/uploads\/2025\/01\/PDF_file_icon.png\" alt=\"\" srcset=\"https:\/\/tiand.top\/wp-content\/uploads\/2025\/01\/PDF_file_icon.png 267w, https:\/\/tiand.top\/wp-content\/uploads\/2025\/01\/PDF_file_icon-244x300.png 244w\" sizes=\"auto, (max-width: 20px) 100vw, 20px\" \/><\/a><\/li>\n<\/ol>\n\n\n\n\n\n<h4 class=\"wp-block-heading has-text-align-center\">Chapters of books<\/h4>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Liu B<sup>*<\/sup>, Zhang Y<sup>*<\/sup>, Zhang C<sup>#<\/sup>, <strong>Tian D<sup>#<\/sup><\/strong>. Cancer Inflammation and Immunity &#8211; Spatial Genomics. <mark style=\"background-color:rgba(0, 0, 0, 0)\" class=\"has-inline-color has-primary-color\">Elsevier. 2024<\/mark> Oct. DOI: 10.1016\/B978-0-443-14064-8.00014-X. <a href=\"https:\/\/tiand.top\/wp-content\/uploads\/2025\/01\/2024_Spatial-genomics.pdf\" target=\"_blank\" rel=\"noreferrer noopener\"><img loading=\"lazy\" decoding=\"async\" width=\"20\" height=\"25\" class=\"wp-image-153\" style=\"width: 20px;\" src=\"https:\/\/tiand.top\/wp-content\/uploads\/2025\/01\/PDF_file_icon.png\" alt=\"\" srcset=\"https:\/\/tiand.top\/wp-content\/uploads\/2025\/01\/PDF_file_icon.png 267w, https:\/\/tiand.top\/wp-content\/uploads\/2025\/01\/PDF_file_icon-244x300.png 244w\" sizes=\"auto, (max-width: 20px) 100vw, 20px\" \/><\/a><\/li>\n<\/ol>\n\n\n\n<p><\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>*\uff1aCo-first author; #\uff1aCo-corresponding author Research Articles Full publications can be seen in Google Scholar. Chapters of books<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-2","page","type-page","status-publish","hentry"],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/tiand.top\/index.php\/wp-json\/wp\/v2\/pages\/2","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/tiand.top\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/tiand.top\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/tiand.top\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/tiand.top\/index.php\/wp-json\/wp\/v2\/comments?post=2"}],"version-history":[{"count":44,"href":"https:\/\/tiand.top\/index.php\/wp-json\/wp\/v2\/pages\/2\/revisions"}],"predecessor-version":[{"id":369,"href":"https:\/\/tiand.top\/index.php\/wp-json\/wp\/v2\/pages\/2\/revisions\/369"}],"wp:attachment":[{"href":"https:\/\/tiand.top\/index.php\/wp-json\/wp\/v2\/media?parent=2"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}