*：Co-first author; #：Co-corresponding author

Representative Research Articles

Full publications can be seen in Google Scholar.

1. Huang S*, Pan L*, Pang S*, Guo H*, Li M, Tian Y, Shi W, Liu B, Wang S, Fan Z, Zong Y^#, Tian D^#, Zhang D^#. Perforin Generated by CD8+ T Cells Exacerbates Inflammatory Bowel Disease–Induced Depression by Promoting CXCL9 Production in Intestinal Epithelial Cells. Gastroenterology. 2025 Aug; 169(2): 294-307. (Front Cover) IF: 26.3
   • Link: Reported by Capital Medical University (Chinese)
   • Link: Reported by Beijing Friendship Hospital (Chinese, detailed description)
   • Link: Reported by stdaily.com中国科技网 (Chinese, science popularization)
2. Tian D, Yang L, Wang S, Zhu Y, Shi W, Zhang C, Jin H, Tian Y, Xu H, Sun G, Liu K, Zhang Z and Zhang D. Double negative T cells mediate Lag3-dependent antigen-specific protection in OVA-induced allergic asthma. Nat Commun. 2019 Sep 18;10(1):4246. IF: 12.1
   • Link: Reported by National Natural Science Foundation of China (Chinese)
3. Yang L*, Zhu Y*, Tian D*, Wang S*, Guo J, Jin H, Zhang C, Shi W, Sun G, Zhang Z, Zhao Y^#, Zhang D^#. Transcriptome landscape of double negative T cells by single-cell RNA sequencing. J Autoimmun. 2021; 121: 102653. IF: 14.5
   • Link: Reported by Capital Medical University (Chinese)
4. Tian D* , Pan Y^*, Zhao Y, Wang H, Tian Y, Yang L, Shi W, Zhang C, Zhu Y, Zhang Y^#, Wang S^#, Zhang D^#, TCRαβ+NK1.1-CD4-CD8- double-negative T cells inhibit central and peripheral inflammation and ameliorate ischemic stroke in mice. Theranostics. 2023, 13(3): 896-909. IF: 12.4
5. Li M*, Pan L*, Zhang Y*, Huang S, Tian Y, Tian D^#, Zhang D^#. Regulatory TCRαβ+ double negative T cells suppress γδ T cells and alleviate colitis. Cell Mol Gastroenterol Hepatol. 2025, 19(10): 101553. IF: 8.2.
6. Tian D#, Qian F#, Pan L#, Yin M, Liu B, Zhang Y, Yang X, Yang L, Sun G, Zhang Z, Wang S, Leungh P, Gershwinh M*, Li C*, Zhang D*, The heterogeneity and sexual-dimorphism of human TCRab+CD4–CD8–double negative T cells. Journal of Genetics and Genomics. 2026, published on line. IF: 7.9
7. Zheng Z#, Zhang Y#, Wang Z#, Liu B#, Yang Y, Pan L, Xin C, Zhang T, Xu R, Zhu D, Zhang Z, Yang Y*, Zhang J*, Tian D*, Single-cell analyses unveils lymph node–tumor ecosystem remodeling during the lymph node metastasis of gastric cancer. Cell Reports. 2026, Accepted. IF: 7.7
8. Qi H* , Tian D* , Zhang C, Jin H, Wang Y, Liu L, Zhao X, Ma L, Duan T^#, Zhang D^#. Foxo3 promotes the differentiation and function of follicular helper T cells. Cell Reports. 2020 May 12. IF: 7.7
9. Shao S#, Han X#, Zhang T, Yang L, Li M, Zhang Z, Du X, Jin H, Wang S, Yang Y, Zhang Z, Sun G*, Zhang D* , Tian D*. FcεRIγ reinforce Double-Negative T cell–mediated Antibody-dependent Cellular Cytotoxicity Against Tumor Cells. Journal of Molecular Cell Biology. 2026, 18: mjaf059. IF: 6.0

Chapters of books

1. Liu B^*, Zhang Y^*, Zhang C^#, Tian D^#. Cancer Inflammation and Immunity – Spatial Genomics. Elsevier. 2024 Oct. DOI: 10.1016/B978-0-443-14064-8.00014-X.