ccmu.edu.cn
Dan Tian was born in Huangshan, Anhui Province, China, in 1989.
Dan Tian received his M.D. and Ph.D. degree in Pathogenic Biology from Harbin Medical University as an eight-year Basic Medicine student in 2015.
He is currently an associated professor, associated researcher, and doctoral supervisor at Beijing Friendship Hospital, Capital Medical University.
He is also the vice director of the General Surgery Laboratory at the National Clinical Research Center for Digestive Diseases and a PI at State Key Lab of Digestive Health, Beijing Friendship Hospital.
Additionally, Dan Tian is an INTJ.
Dan Tian’s recent research focuses on neuroimmune and immunometabolism in inflammation and tumors of the digestive system. His team unraveled the role of perforin in inflammatory bowel disease (IBD) and IBD-induced depression via gut-brain axis (Gastroenterology, 2025; J Inflamm Res, 2025) and NAD-induced intestinal T cell activation via P2X7R in postoperative ileus (Cell Immunol, 2023). He aims to further explore the elaborate roles of residential immune cell in the progression of digestive diseases.
Another aspect of his works focuses on the regulatory mechanisms and applications of a novel unconventional T cell subset, double negative T (DNT, CD3+TCRαβ+NK1.1–CD4−CD8−) cells, in autoimmunity and digestive diseases. His previous studies demonstrated that the adoptive transfer of DNT cells prevent immune-related diseases, such as allergic asthma and IBD (Nat Commun, 2019; Cell Mol Gastroenterol Hepatol, 2025) and both systemic and local secondary inflammation induced by ischemic stroke (Theranostics, 2023).
Research Interest
Intestinal Immunology; Neuroimmunology; Tumor immunology
Other Links
Personal introduction page in Graduate School of Capital Medical University (Chinese)
Personal Introduction page in the news of Beijing Friendship Hospital (Chinese)